MOTS-c 5mg

MOTS-c Peptide 5mg: Exploring the Frontiers of Mitochondrial Signaling

MOTS-c is a 16-amino acid peptide (Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg) that has redefined our understanding of how mitochondria communicate with the rest of the cell. Often referred to as a “mitochondrial-derived peptide” (MDP), it acts as a metabolic hormone that translocates to the nucleus in response to metabolic stress. Researchers searching for MOTS-c for sale trust Peptide Sciences for the chemical stability and high purity required to investigate how this peptide regulates nuclear gene expression and systemic energy balance.

What is MOTS-c?

MOTS-c is uniquely encoded within the 12S rRNA gene of the mitochondrial genome. It serves as a signaling molecule that coordinates mitochondrial function with nuclear activity, helping the cell adapt to changes in nutrient availability and physical stress.

How Does MOTS-c Work in Laboratory Models?

In preclinical studies, MOTS-c is investigated for its role as a metabolic master regulator. Its primary mechanism of action involves the activation of the AMPK (AMP-activated protein kinase) pathway, which is the cell’s central sensor for energy status.

• AMPK Activation: Researching how MOTS-c increases glucose uptake and fatty acid oxidation without increasing insulin levels.

• Mitochondrial Homeostasis: Studying the peptide’s ability to promote mitochondrial biogenesis and maintain the integrity of the mitochondrial network.

• Stress Adaptation: Investigating how MOTS-c translocates to the nucleus during metabolic stress to regulate the transcription of adaptive stress-response genes.

Key Research Applications in Metabolism and Aging

Because of its role in energy regulation, MOTS-c is a cornerstone of modern aging and metabolic research:

• Metabolic Signaling Mechanisms: Understanding the “mitonuclear” communication pathways that govern systemic metabolic health.

• Aging and Longevity Research: Investigating how MOTS-c levels correlate with aging and its potential to influence cellular senescence in animal models.

• Energy Regulation: Studying the peptide’s impact on insulin sensitivity and lipid metabolism in models of metabolic dysfunction.

• Exercise Mimetic Studies: Researching how MOTS-c mimics the metabolic benefits of physical activity at the cellular level.

Why Choose the Peptide Sciences Official Store?

Reliable metabolic research requires reagents that are free from structural degradation and environmental contaminants. PeptideScience ensures your laboratory has the high-quality compounds necessary for reproducible results.

• Verified 99%+ Purity: Every 5mg vial of MOTS-c is tested via HPLC-MS to ensure precise amino acid sequence and purity.

• Full Lab Transparency: We include a Certificate of Analysis (COA) with every order, providing verified documentation for your records.

• Discreet & Secure Logistics: We prioritize private, secure shipping to ensure your research materials arrive in optimal condition.

• Bulk Savings: Use an official Peptide Sciences coupon at checkout for competitive pricing on high-volume laboratory orders.

Note: MOTS-c is provided for Laboratory Research Use Only. It is not intended for human or animal consumption. Please ensure all safety and handling protocols are strictly followed in your facility.